Effects of ciprofloxacin on ethanol pharmacokinetics
| Before CIP | After CIP | p Value | |
|---|---|---|---|
| Peak ethanol (mM) | 22.47 (1.00) | 23.27 (1.26) | NS |
| Vd(l/kg) | 0.70 (0.02) | 0.70 (0.02) | NS |
| C0(mM) | 19.68 (0.54) | 19.71 (0.58) | NS |
| EER (mg/kg/h) | 107.0 (5.3) | 96.9 (4.8) | 0.001 |
| AUC (mM/h) | 58.9 (2.9) | 65.5 (3.3) | 0.0004 |
| Time 0 (h) | 5.99 (0.31) | 6.61 (0.32) | 0.0003 |
Results expressed as mean (SEM).
CIP, ciprofloxacin.