Clinical characteristics of 32 HIV-1 infected patients investigated for small bowel bacterial overgrowth
Clinical feature | Diarrhoea (n=21) | No diarrhoea (n=11) |
Risk group | ||
Homosexual | 19 (90) | 9 (82) |
Heterosexual | 2 (10) | 1 (9) |
Intravenous drug use | 0 | 1 (9) |
Prior opportunistic infection | 12 (57) | 5 (45) |
Antiretroviral therapy | 17 (81) | 7 (64) |
Duration of diarrhoea (mean no of weeks) | 15 | NA |
Number of stools/day (mean) | 9 | NA |
Indications for endoscopy | ||
Diarrhoea | 21 (100) | 0 |
Oesophageal symptoms | 0 | 7 (64) |
Epigastric pain | 0 | 2 (18) |
Staging of Kaposi’s sarcoma | 0 | 2 (18) |
Pneumocystis carinii prophylaxis | ||
Trimethoprim-sulphamethoxazole | 12 (57) | 9 (82) |
Dapsone | 6 (29) | 0 |
Azithromycin | 3 (14) | 0 |
CD4 lymphocyte count, median (range) | 20 (2–828) | 50 (1–353) |
Values in parentheses are percentages except where otherwise indicated.
NA, not applicable.