Familial Crohn’s disease (n=152) | Sporadic Crohn’s disease (n=1164) | p Value | |
Male/female | 63/89 | 458/706 | NS |
Age at diagnosis (years)3-150 | 26.8 (12.1) | 28.9 (12.9) | 0.06 |
Delay between onset of symptoms and diagnosis (months)3-150 | 19.1 (37.5) | 15.8 (32.8) | NS |
Mean duration of illness (months)3-150 | 125 (112) | 92 (88) | 0.0005 |
Ethnicity | |||
Non-Jewish whites | 88 (58%) | 927 (80%) | <10-6 |
Jews | 43 (28%) | 126 (11%) | <10-6 |
Arabs | 19 (12%) | 83 (7%) | 0.02 |
Asians | 0 | 2 (0.2%) | NS |
Blacks | 2 (1%) | 26 (2%) | NS |
Smoking status | |||
Smokers | 85 (56%) | 626 (54%) | NS |
Non-smokers | 57 (37%) | 420 (36%) | NS |
Unknown | 10 (7%) | 118 (10%) | NS |
Initial site of disease | |||
Colon only | 43 (28%) | 381 (33%) | NS |
Small bowel only | 42 (28%) | 372 (32%) | NS |
Small bowel and colon | 65 (43%) | 399 (34%) | 0.04 |
Other | 2 (1%) | 12 (1%) | NS |
Anoperineal disease at onset | 25 (16%) | 252 (22%) | NS |
Extra-intestinal manifestations | 57 (38%) | 422 (36%) | NS |
↵3-150 Mean (SD).