Table 1

Morphology and myeloperoxidase activity (MPO) of colonic tissue at three time points after intracolonic administration of TNBS (80 mg/kg), ethanol (40%), or saline

Day
2615
Gross damage score
 Saline000
 Ethanol2.4 (0.2)* NDND
 TNBS13.7 (0.6) 11.8 (0.4) 4.4 (0.7)*
MPO (U/g tissue)
 Saline1.3 (0.4)1.6 (0.2)2.0 (0.4)
 Ethanol18.4 (3.5)* NDND
 TNBS35.1 (3.5) 52 (5.5) 6.2 (2.8)
  • Values are means (SEM) of 5–6 rats.

  • Different symbols denote a significant difference between groups, p<0.05.

  • ND, not determined.