Risk of extracolonic cancers in first degree relatives of the comparison (group 1) and study (group 2) groups compared with the general population
| Extracolonic tumours | |||||||
|---|---|---|---|---|---|---|---|
| HNPCC | Non-HNPCC | ||||||
| Observed | Expected | RR | Observed | Expected | RR | ||
| Group 1 | 67 | 78.1 | 0.9 | 218 | 252.5 | 0.9 | |
| Group 2 | 32 | 14.8 | 2.19-150 | 77 | 67.2 | 1.1 | |
Cancers associated with HNPCC include those of stomach, small bowel, endometrium, ovary, and urinary tract.
↵9-150 Significant result using Poisson distribution (p<0.001).