Table 1

The effects of pyrrolidine dithiocarbonate (PDTC) on serum amylase and packed cell volume in rats with taurocholate (TCA) pancreatitis

Serum amylase after 12 hours (IU/l)Packed cell volume (%)
12 h24 h
Control10 228.0 (723.1)43.5 (2.1)44.5 (2.5)
TCA pancreatitis
 Without PDTC19 434.2 (2117.7)56.5 (3.2)59.6 (3.3)
 With PDTC18 476.4 (1906.7)49.5 (2.3)1-150 46.5 (4.8)1-150
  • Results are expressed as mean (SEM).

  • Rats were treated with or without 10 mg/kg PDTC one hour before the induction of TCA pancreatitis. Control rats received intraductal infusion of saline as described in experimental design. The number of rats in each group was 16.

  • 1-150 p<0.05 compared with no PDTC (unpaired Student’st test).