Table 5

Sigmoidoscopy and rectal biopsy findings

IBS+ (n=10)IBS− (n=19)Controls (n=18)
Mean (SD) age, years39.2 (19.1)46.8 (16.6)30.1 (10.2)
No of female subjects (%)4 (40) 7 (37) 14 (78)
No received antibiotics (%)8 (80)13 (62)
No of positive stool cultures (%)6 (60)10 (53)
Acute infection biopsy samples
Mean (SD) interval from onset to biopsy, days10.6 (18.6)5.1 (4.6)
No of patients with macroscopic colitis (%)3 (30)7 (37)0 (0)
No of biopsy specimens with acute inflammatory changes (%)3 (30)3 (16)0 (0)
Mean (SD) no of chronic inflammatory cells per hpf 98.4 (17.4) 99.8 (35.0) 79.1 (16.9)
Postinfection biopsy samples
Mean (SD) interval from onset to biopsy, days106.4 (36.2)105.6 (25.9)
No of patients with macroscopic colitis (%)0 (0)0 (0)0 (0)
No of biopsy specimens with acute inflammatory changes (%)2 (20)2 (11)0 (0)
Mean (SD) no of chronic inflammatory cells per hpf 105.7 (23.3)9-150 83.2 (29.4)79.1 (16.9)
  • 9-150 p<0.05 versus IBS−; p<0.05 versus normal controls;p<0.01 versus normal controls.