Placebo | Omeprazole (10 mg) | Total | ||
Total no of patients | n | 150 | 150 | 300 |
Age (y) | n | 150 | 150 | 150 |
Missing | 0 | 0 | 0 | |
Mean | 53.5 | 54.8 | 54.1 | |
SD | 14.7 | 14.1 | 14.4 | |
Sex | ||||
Male | n | 103 | 103 | 206 |
Female | n | 47 | 47 | 94 |
Body mass index | ||||
Male | n | 100 | 102 | 202 |
Missing | 3 | 1 | 4 | |
Mean | 26.2 | 26.1 | 26.2 | |
SD | 4.0 | 3.1 | 3.6 | |
Female | n | 45 | 43 | 88 |
Missing | 2 | 4 | 6 | |
Mean | 28.1 | 26.5 | 27.3 | |
SD | 4.3 | 4.0 | 4.2 | |
Ethnic origin | ||||
Caucasian | n | 150 | 147 | 297 |
Other | n | 0 | 3 | 3 |
Smoking | ||||
No | n | 107 | 108 | 215 |
Yes | n | 43 | 43 | 85 |
Alcohol Consumption | ||||
No | n | 41 | 53 | 94 |
Yes | n | 109 | 97 | 206 |
Duration of reflux history (y) | n | 106 | 94 | 200 |
Missing1-150 | 44 | 56 | 100 | |
Mean | 2.6 | 2.9 | 2.7 | |
SD | 3.9 | 4.0 | 4.0 | |
Duration of current symptoms (m) | n | 148 | 150 | 298 |
Missing | 2 | 0 | 2 | |
Mean | 7.7 | 7.8 | 7.8 | |
SD | 9.1 | 9.6 | 9.3 | |
On H2 receptor antagonist at time of entry to study | n | 77 | 69 | |
Grade of oesophagitis1-151 | ||||
2 | n | 75 | 62 | 137 |
3 | n | 57 | 65 | 122 |
4 | n | 18 | 23 | 41 |
↵1-150 In most of these patients, reasonably accurate information could not be obtained.
↵1-151 Oesophagitis grading scale (Maratka6a): 0, normal oesophageal mucosa, no abnormalities noted; 1, no macroscopic erosions visible, mucosa is erythematous, oedema causes accentuated folds; 2, isolated round or linear erosions extending from the squamocolumnar junction upwards in relation to the folds but not involving the whole circumference; 3, confluent erosions involving the entire circumference of superficial ulceration; 4, erosions as described above plus deep ulceration.