Prevalence of genetic alterations compared with size, histopathology, and site of adenomas
| K-ras mutation | p53 overexpression | Loss of 18q | RER positive | |
|---|---|---|---|---|
| Size in cm | ||||
| 0.1–0.5 | 31 (39/125) | 6 (8/126) | 3 (3/110) | 5 (5/110) |
| >0.5–1 | 40 (20/50) | 4 (2/50) | 0 (0/43) | 12 (5/43) |
| >1 | 44 (11/25) | 12 (3/25) | 4 (1/23) | 13 (3/23) |
| Histopathology | ||||
| Tubular | 33 (52/158) | 3 (5/158) | 3 (4/139) | 6 (8/139) |
| Tubulovillous | 41 (17/40) | 20 (8/41)3-150 | 0 (0/35) | 14 (5/35) |
| Villous | 50 (1/2) | 0 (0/2) | 0 (0/2) | 0 (0/2) |
| Site | ||||
| Right | 34 (35/102) | 3 (3/102) | 1 (1/89) | 9 (8/89) |
| Left | 35 (33/94) | 11 (10/95) | 4 (3/84) | 6 (5/84) |
Results are expressed as % (fraction).
↵3-150 p=0.001, villous and tubulovillous versus tubular adenomas.