Table 8

Characteristics of the 251 patients in the valid for efficacy analysis

CharacteristicsTotal (n=251)Placebo (n=90)O1 (n=78)O2 (n=83)
Sex (M/F)169/8254/3658/2057/26
Age
Mean50.654.348.548.7
 Range18–9319–9318–8421–80
Aetiology
Alcohol103 (41%)33 (37%)33 (42%)37 (45%)
 Gallstones96 (38%)37 (41%)29 (37%)30 (36%)
 Alcohol + gallstones2 (0.8%)002 (2%)
 Alcohol + others2 (0.8%)01 (1%)1 (1%)
 Others48 (19%)20 (22%)15 (19%)13 (16%)
Duration of pain (hours)11-150 44 (4–96)46 (5–96)44 (7–96)44 (4–96)
Severity of disease11-151
Ranson score3 (0–9)4 (1–8)3 (1–8)3 (0–9)
 Apache II score7 (0–37)7 (0–28)7 (0–22)9 (0–37)
 Complication score6 (1–27)6 (1–20)6 (1–27)6 (1–27)
 C-reactive protein145 (0–777)154 (0–438)134 (2–777)146 (1–510)
CT findings11-152
Normal pancreas1 (0.4%)1 (1%)00
 Oedema19 (8%)9 (10%)2 (3%)8 (10%)
 Oedema + exudate115 (46%)44 (49%)42 (54%)29 (35%)
 Necrosis <30%60 (24%)22 (24%)15 (19%)23 (28%)
 Necrosis <50%19 (8%)2 (2%)10 (13%)7 (8%)
 Necrosis >50%9 (4%)2 (2%)3 (4%)4 (5%)
 Not performed28 (11%)10 (11%)6 (8%)12 (14%)
 Total251 (100%)90 (100%)78 (100%)83 (100%)
  • 11-150 Until enrolment; median values (range).

  • 11-151 Median values (range).

  • 11-152 CT findings within 96 hours of onset of symptoms.