Characteristics of the 251 patients in the valid for efficacy analysis
| Characteristics | Total (n=251) | Placebo (n=90) | O1 (n=78) | O2 (n=83) |
|---|---|---|---|---|
| Sex (M/F) | 169/82 | 54/36 | 58/20 | 57/26 |
| Age | ||||
| Mean | 50.6 | 54.3 | 48.5 | 48.7 |
| Range | 18–93 | 19–93 | 18–84 | 21–80 |
| Aetiology | ||||
| Alcohol | 103 (41%) | 33 (37%) | 33 (42%) | 37 (45%) |
| Gallstones | 96 (38%) | 37 (41%) | 29 (37%) | 30 (36%) |
| Alcohol + gallstones | 2 (0.8%) | 0 | 0 | 2 (2%) |
| Alcohol + others | 2 (0.8%) | 0 | 1 (1%) | 1 (1%) |
| Others | 48 (19%) | 20 (22%) | 15 (19%) | 13 (16%) |
| Duration of pain (hours)11-150 | 44 (4–96) | 46 (5–96) | 44 (7–96) | 44 (4–96) |
| Severity of disease11-151 | ||||
| Ranson score | 3 (0–9) | 4 (1–8) | 3 (1–8) | 3 (0–9) |
| Apache II score | 7 (0–37) | 7 (0–28) | 7 (0–22) | 9 (0–37) |
| Complication score | 6 (1–27) | 6 (1–20) | 6 (1–27) | 6 (1–27) |
| C-reactive protein | 145 (0–777) | 154 (0–438) | 134 (2–777) | 146 (1–510) |
| CT findings11-152 | ||||
| Normal pancreas | 1 (0.4%) | 1 (1%) | 0 | 0 |
| Oedema | 19 (8%) | 9 (10%) | 2 (3%) | 8 (10%) |
| Oedema + exudate | 115 (46%) | 44 (49%) | 42 (54%) | 29 (35%) |
| Necrosis <30% | 60 (24%) | 22 (24%) | 15 (19%) | 23 (28%) |
| Necrosis <50% | 19 (8%) | 2 (2%) | 10 (13%) | 7 (8%) |
| Necrosis >50% | 9 (4%) | 2 (2%) | 3 (4%) | 4 (5%) |
| Not performed | 28 (11%) | 10 (11%) | 6 (8%) | 12 (14%) |
| Total | 251 (100%) | 90 (100%) | 78 (100%) | 83 (100%) |