Table 2

Combined analysis of HLA-DR antigens in relation to inflammatory bowel disease

HLA-DR antigenNumber of studiesOR (95% CI)
Main Split CD UC CD UC
DR114130.90 (0.64–1.26)1.08 (0.81–1.44)
DR215170.83 (0.70–0.98)2.00 (1.52–2.63)
DR15461.13 (0.91–1.40)1.65 (1.22–2.25)
DR16460.67 (0.30–1.51)0.59 (0.30–1.23)
DR312130.71 (0.56–0.90)0.83 (0.63–1.09)
DR415151.18 (0.89–1.56)0.54 (0.43–0.68)
DR514141.18 (0.99–1.42)1.22 (0.93–1.60)
DR11641.03 (0.82–1.29)1.09 (0.66–1.80)
DR12641.15 (0.75–1.77)1.06 (0.30–4.12)
DR614121.07 (0.89–1.27)0.82 (0.60–1.12)
DR13651.23 (0.99–1.51)0.82 (0.52–1.29)
DR14650.79 (0.48–1.30)0.95 (0.56–1.63)
DR712111.42 (1.16–1.74)0.87 (0.66–1.14)
DR814111.11 (0.82–1.49)1.03 (0.72–1.47)
DR912121.12 (0.63–1.98)1.54 (1.06–2.24)
DR10981.65 (0.91–2.98)0.55 (0.23–1.30)
DR10333.42 (1.52–7.69)
  • CD, Crohn’s disease; UC, ulcerative colitis; OR, odds ratio; CI, confidence interval.