Histology of the gastric corpus in patients with and controls without reflux oesophagitis
| 1 Oesophagitis and Barrett’s (n=154) | 2 Erosive oesophagitis (n=116) | 3 Control subjects (n=148) | 1 versus 3 p value | 2 versus 3 p value | |
|---|---|---|---|---|---|
| Acute gastritis | |||||
| Grade 0 | 115 (75%) | 94 (81%) | 94 (64%) | 0.0383 | 0.0013 |
| Grade 1 | 32 (21%) | 20 (17%) | 37 (25%) | ||
| Grade 2 | 7 (5%) | 2 (2%) | 17 (11%) | ||
| Chronic gastritis | |||||
| Grade 0 | 80 (52%) | 66 (57%) | 52 (35%) | 0.0116 | 0.0011 |
| Grade 1 | 52 (34%) | 38 (33%) | 64 (43%) | ||
| Grade 2 | 22 (14%) | 12 (10%) | 32 (22%) | ||
| Atrophy | |||||
| Grade 0 | 151 (98%) | 115 (99%) | 136 (92%) | 0.0357 | 0.0249 |
| Grade 1 | 3 (2%) | 1 (1%) | 9 (6%) | ||
| Grade 2 | 0 (0%) | 0 (0%) | 3 (2%) | ||
| Intestinal metaplasia | |||||
| Absent | 147 (95%) | 111 (96%) | 135 (91%) | 0.1387 | 0.1524 |
| Present | 7 (5%) | 5 (4%) | 13 (9%) | ||
| H pylori infection | |||||
| Grade 0 | 101 (66%) | 80 (69%) | 93 (63%) | 0.6078 | 0.5330 |
| Grade 1 | 37 (24%) | 27 (23%) | 39 (26%) | ||
| Grade 2 | 16 (10%) | 9 (8%) | 16 (11%) | ||