Risk factors for reflux oesophagitis
| Risk factor | Odds ratio | 95% confidence interval | Wald’s χ2 | p Value |
|---|---|---|---|---|
| Outcome: oesophagitis and Barrett’s oesophagus | ||||
| Age (per decade) | 1.22 | (1.01–1.48) | 4.297 | 0.0382 |
| Sex (male versus female) | 2.10 | (1.19–3.73) | 6.466 | 0.0110 |
| Smoking status | 1.94 | (1.06–3.56) | 4.586 | 0.0322 |
| Chronic corpus gastritis | 0.46 | (0.27–0.79) | 7.925 | 0.0049 |
| Outcome: erosive oesophagitis alone | ||||
| Age (per decade) | 1.27 | (1.03–1.56) | 5.022 | 0.0250 |
| Sex (male versus female) | 2.03 | (1.07–3.84) | 4.702 | 0.0301 |
| Smoking status | 1.50 | (0.77–2.94) | 1.427 | 0.2323 |
| Chronic corpus gastritis | 0.34 | (0.19–0.61) | 12.803 | 0.0003 |
Odds ratios and their significance were calculated by multiple logistic regression analysis, using as outcome variable all types of reflux disease or erosive oesophagitis alone.