Table 1

Patient characteristics

Number of patientsMedian age (range) (years)SexMedian duration of symptoms (range) (months)Site of fissure
AnteriorPosterior
Placebo2236 (22–54)12F, 10M8 (4–24)517
0.2% GTN2335 (22–81)12F, 11M8 (4–36)617
Variable dose GTN2336 (21–72)9F, 14M7 (3–24)320