Changes in pressure, length, and position of the gastro-oesophageal junction high pressure zone caused by Müller manoeuvre
| Normal subjects | Hiatus hernia | ||||
|---|---|---|---|---|---|
| HPZ 1 (proximal) | HPZ 2 (hiatal) | ||||
| Intragastric pressure change (mm Hg) | 10 (2) | – | 8 (1) | ||
| Distal oesophageal pressure change (mm Hg) | −5 (2.0) | −5 (1.5) | – | ||
| Increase in maximal pressure (mm Hg) | 27 (1.3) | −3 (0.2)5-150 | 24 (1.4) | ||
| Length change of high pressure zone (cm) | −0.8 (0.2) | 0.4 (0.1)5-150 | 0.3 (0.1)5-150 | ||
| Movement of locus of maximal pressure (cm) | −2.2 (0.5) | −0.6 (0.2)5-150 † | −1.8 (0.4) | ||
| Movement of squamocolumnar junction (cm) | −1.1 (0.3) | −0.4 (0.2)5-150 | – | ||
| Movement of hiatal centre (cm) | −1.7 (0.4) | – | −1.8 (0.4) | ||
Changes in the hiatus hernia patients were measured both within the proximal high pressure zone (HPZ 1) and the hiatal canal (HPZ 2).
All values are mean (SEM).
↵5-150 p<0.05 versus normal; †p<0.05 versus movement of HPZ 2.