Table 2

Patients with grade 3 or 4 iron staining (explant liver)

	Pretransplant			Explant		HFE analysis
OLT number	Histological iron grade I (0–4)	Transferrin saturation^*	Serum ferritin^†	Spur cell haemolytic anaemia	Units transfused before surgery	Histological iron grade I (0–4)	Hepatic iron concentration^‡	Hepatic iron index^§	C282Y	H63D
425	–	62	330	No	–	3	88	1.95	CC	HD
373	–	44	365	No	–	3	102	2.54	CC	HH
392	2^2-160	74	510	Yes	2	3 (2–3+)	130	1.87	CC	HH
432	4^2-160	97	2980	Yes	4	4	54	1.35	CC	HH
276	–	87	1036	Yes	–	4 (2–4)	55	0.93	CC	HH
296	3^2-160	84	1380	Yes	10	4 (2–4)	95	1.70	CC	HH
401	2	76	1200	Yes	4	4 (3–4)	170	3.40	CC	HD
313	–	84	1775	Yes	17	4 (3–4)	232	5.10	CC	HH

Normal values: ^*15–55%; ^†25–350 μl; ^‡<25 μmol/g;^§<1.9.
↵2-160 Transjugular liver biopsy.
HFE: C282Y gene mutation (CC = homozygous normal); H63D gene mutation (HH = homozygous normal, HD = heterozygous).
HII, hepatic iron index (μmol/g dry weight/age in years).3
I, histological assessment.20