Pretransplant | Explant | HFE analysis | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OLT number | Histological iron grade I (0–4) | Transferrin saturation* | Serum ferritin† | Spur cell haemolytic anaemia | Units transfused before surgery | Histological iron grade I (0–4) | Hepatic iron concentration‡ | Hepatic iron index§ | C282Y | H63D | ||
425 | – | 62 | 330 | No | – | 3 | 88 | 1.95 | CC | HD | ||
373 | – | 44 | 365 | No | – | 3 | 102 | 2.54 | CC | HH | ||
392 | 22-160 | 74 | 510 | Yes | 2 | 3 (2–3+) | 130 | 1.87 | CC | HH | ||
432 | 42-160 | 97 | 2980 | Yes | 4 | 4 | 54 | 1.35 | CC | HH | ||
276 | – | 87 | 1036 | Yes | – | 4 (2–4) | 55 | 0.93 | CC | HH | ||
296 | 32-160 | 84 | 1380 | Yes | 10 | 4 (2–4) | 95 | 1.70 | CC | HH | ||
401 | 2 | 76 | 1200 | Yes | 4 | 4 (3–4) | 170 | 3.40 | CC | HD | ||
313 | – | 84 | 1775 | Yes | 17 | 4 (3–4) | 232 | 5.10 | CC | HH |
Normal values: *15–55%; †25–350 μl; ‡<25 μmol/g;§<1.9.
↵2-160 Transjugular liver biopsy.
HFE: C282Y gene mutation (CC = homozygous normal); H63D gene mutation (HH = homozygous normal, HD = heterozygous).
HII, hepatic iron index (μmol/g dry weight/age in years).3
I, histological assessment.20