Table 1

Transepithelial resistance (TER) in the presence of apical and/or basolateral cytokine

IFN-γTNF-αnTER at 24 hTER at 48 h
41.26 (0.08)1.16 (0.09)
a,b41.21 (0.15)1.12 (0.23)
a51.89 (0.15)1.46 (0.14)
b60.79 (0.06)0.14 (0.02)1-150
ba60.79 (0.11)0.15 (0.03)1-150
bb70.28 (0.04)1-150 0.14 (0.01)1-150
a,ba,b70.27 (0.04)1-150 0.13 (0.01)1-150
  • Confluent T84 monolayers were cultured with interferon (IFN) γ 100 ng/ml and/or tumour necrosis factor (TNF) α 1 ng/ml. Cytokine was present in the apical media (a) or the basolateral media (b). TER was measured after 24 hours of culture and again after 48 hours and is expressed relative to the initial TER of each monolayer. The average initial TER was 2100 (100) ohms·cm2. Data are from two experiments and are expressed as means (SEM).

  • 1-150 TER was significantly different from control (p<0.05).