Microsatellite instability and mutator gene mutations in HNPCC and suspected HNPCC families
| Microsatellite instability | DNA mismatch repair gene mutations | ||||
|---|---|---|---|---|---|
| Type of family | Positive | Negative | MSH2 | MLH1 | |
| HNPCC (n=18) | 11 (61)2-150 | 7 | 2 | 1 | |
| Suspected HNPCC (n=18) | 4 (22) | 14 | – | – | |
Values in parentheses are percentages.
↵2-150 χ2 = 5.6, p = 0.02.