Table 4

Prevalence and titre of non-organ-specific autoantibodies (NOSA) within the different classes of hepatitic C virus (HCV) genotypes

ANASMAANA + SMALKM1AMATotal NOSA
HCV RNA positive184-150 (11.1)134-150 (8.0)3 (1.8)3 (1.8)1 (0.6)384-150 (23.5)
Genotype 1a (n=7)0 (0)1 (14.3)0 (0)0 (0)0 (0)1 (14.3)
Genotype 1b (n=68)4 (5.9)7 (10.3)1 (1.5)2 (2.9)1 (1.5)15 (22)
Genotype 2a (n=39)4 (10.3)2 (5.1)0 (0)0 (0)0 (0)6 (15.4)
Genotype 2b (n=1)1 (100)0 (0)0 (0)0 (0)0 (0)1 (100)
Genotype 2c (n=4)0 (0)0 (0)1 (25)0 (0)0 (0)1 (25)
Genotype 3a (n=3)0 (0)0 (0)0 (0)0 (0)0 (0)0 (0)
Genotype untypable (n=26)5 (19)2 (7.7)1 (3.8)1 (3.8)0 (0)9 (34.6)
Two or three genotypes (n=14)4 (36.4)1 (9.1)0 (0)0 (0)0 (0)5 (35.7)
  • Values in parentheses are percentages.

  • 4-150 p<0.05 v other groups.

  • ANA, anti-nuclear antibodies; SMA, anti-smooth muscle antibodies; LKM1, anti-liver/kidney microsomes type 1 antibodies; AMA, anti-mitochondrial antibodies.