Prevalence and titre of non-organ-specific autoantibodies (NOSA) within the different classes of hepatitic C virus (HCV) genotypes
| ANA | SMA | ANA + SMA | LKM1 | AMA | Total NOSA | |
|---|---|---|---|---|---|---|
| HCV RNA positive | 184-150 (11.1) | 134-150 (8.0) | 3 (1.8) | 3 (1.8) | 1 (0.6) | 384-150 (23.5) |
| Genotype 1a (n=7) | 0 (0) | 1 (14.3) | 0 (0) | 0 (0) | 0 (0) | 1 (14.3) |
| Genotype 1b (n=68) | 4 (5.9) | 7 (10.3) | 1 (1.5) | 2 (2.9) | 1 (1.5) | 15 (22) |
| Genotype 2a (n=39) | 4 (10.3) | 2 (5.1) | 0 (0) | 0 (0) | 0 (0) | 6 (15.4) |
| Genotype 2b (n=1) | 1 (100) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (100) |
| Genotype 2c (n=4) | 0 (0) | 0 (0) | 1 (25) | 0 (0) | 0 (0) | 1 (25) |
| Genotype 3a (n=3) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Genotype untypable (n=26) | 5 (19) | 2 (7.7) | 1 (3.8) | 1 (3.8) | 0 (0) | 9 (34.6) |
| Two or three genotypes (n=14) | 4 (36.4) | 1 (9.1) | 0 (0) | 0 (0) | 0 (0) | 5 (35.7) |
Values in parentheses are percentages.
↵4-150 p<0.05 v other groups.
ANA, anti-nuclear antibodies; SMA, anti-smooth muscle antibodies; LKM1, anti-liver/kidney microsomes type 1 antibodies; AMA, anti-mitochondrial antibodies.