Table 1

Haplotype sharing in concordant affected sibs with Crohn’s disease

Affected sib pairs
Number of haplotypes shared012Total
Observed number of sib pairs4301852
Expected number of sib pairs13261352
χ2=8.769, df=2, p=0.013 (for sharing zero, one, and two)
χ2=8.308, df=1, p=0.004 (for sharing zerov sharing at least one)
Affected sib trios
Number of haplotypes shared by all three affected sibs012Total
Observed number of sib trios2327
Expected number of sib trios3.942.630.447