Effect of pentoxifylline (PF) treatment
| Villous length (μm) | Crypt depth (μm) | Crypt:villous ratio | Apoptotic cells/HPF | |
|---|---|---|---|---|
| Syngeneic control | 310 (29) | 94 (9) | 0.31 | 1.1 (0.5) |
| GVHD | 198 (21) | 176 (11) | 0.88 | 35 (7) |
| GVHD + PF | 279 (25) | 109 (15) | 0.37 | 2.3 (2) |
Villous length and crypth depth were measured after six days by a graded ocular in at least 10 complete, 10 semiallogenic untreated, and six pentoxifylline treated animals. Data represent the average (SD) of these measurements.
HPF, high power field; GVHD, graft versus host disease.