Table 3

Change in symptom score (scale 0–3), between 0 and 24 months

OmeprazoleRanitidinep Value3-151
Study completed (n)2627
Heartburn−1.083-150 (−1.65 to −0.51)−0.673-150 (−1.10 to −0.23)0.13
Regurgitation−0.503-150 (−0.90 to −0.10)−0.703-150 (−1.16 to −0.25)0.48
Dysphagia0.0 (−0.15 to +0.15)−0.11 (−0.31 to +0.09)0.30
Odynophagia−0.19 (−0.43 to +0.05)−0.11 (−0.31 to +0.09)0.73
  • Results expressed as mean values (95% confidence interval), non-parametric.

  • 3-150 Statistically significant according to Pitman.

  • 3-151 Omeprazole v ranitidine; according to Yates and Cochran.