Table 5

Change in surface area (absolute and relative) of Barrett’s oesophagus, expressed as the area under the curve (AUC), derived from measurements at 0, 3, 9, 15, and 24 months, compared with no change

Omeprazole (n=26)Ranitidine (n=27)p Value5-151
AUC—change in area (squares/month)−8625-150(−1466 to −302)−11 (−312 to +236)0.02
AUC—relative change in area (%/month)−9.05-150 (−15.0 to −3.0)+0.1 (−3.6 to +2.8)0.02
  • Results expressed as mean values (95% confidence interval).

  • 5-150 Statistically significant, non-parametric paired Wilcoxon.

  • 5-151 Omeprazole v ranitidine; Mann-Whitney U test.