Median age at onset of symptoms and diagnosis in parents and children with inflammatory bowel disease
| Families with CD only (n=50) | Families with UC only (n=51) | Mixed disease families (n=36) | All families (n=137) | |
|---|---|---|---|---|
| Age at onset of symptoms (y) | ||||
| Parents | 31.51-150 | 401-150 | 37.51-150 | 38 |
| Children | 18.5 | 24 | 21.5 | 22 |
| Age at diagnosis (y) | ||||
| Parents | 391-150 | 411-150 | 401-150 | 41 |
| Children | 21.5 | 25 | 22 | 23 |
| Predicted age at diagnosis (y) | ||||
| Parents | 47.51-150 | 461-150 | 461-150 | 47 |
| Children | 26 | 28.5 | 22.5 | 27 |
| Time interval between onset of symptoms and diagnosis (y) | ||||
| Parents | 7.5 | 1 | 2.5 | 3 |
| Children | 3 | 1 | 0.5 | 1 |
The predicted age of diagnosis was calculated using data obtained from the control group of patients with non-familial disease (see text for details).
↵1-150 Difference between parents and children, p<0.001.
CD, Crohn’s disease; UC, ulcerative colitis.