First symptoms of acute pancreatitis not more than 96 hours before enrolment |
Serum amylase or lipase increased at least threefold during this period |
Spontaneous upper abdominal pain during this period |
Written informed consent to participate in the study1-150 |
Supporting criteria (fulfilment of at least four required) |
Local abdominal resistance |
Subileus/ileus |
Shock: pulse ⩾100/min and systolic blood pressure ⩽80 mm Hg for more than 10 minutes |
Arterial Po
2 <60 mm Hg |
Leucocyte count >12 g/l |
C-reactive protein >120 mg/l |
Fasting blood glucose >8.4 mmol/l1-151 |
Hypocalcaemia ⩽2.0 mmol/l |
Serum creatinine >240 μmol/l |
Characteristic findings of moderate or severe acute pancreatitis on ultrasound or contrast enhanced CT |