Table 4

Median (range) plasma homocysteine (tHcy) concentrations in patients with inflammatory bowel disease (IBD) and normal healthy controls stratified by MTHFR C677T variant

tHcy (μmol/l)
Genotype IBD Controls p Value
TT12.91 (3.20–39.24)n=3011.56 (8.70–14)n=70.16
CT10.47 (5.54–38) n=709.07 (6.33–14.56)n=380.06
CC10.50 (1.56–36.40)n=728.96 (5.41–13.75)n=420.01
  • IBD: TT versus CT, p=0.02; TT versus CC, p=0.03.

  • Controls: TT versus CT, p=0.14; TT versus CC, p=0.03.