Table 5

Median (range) plasma folate (PF) concentrations in patients with inflammatory bowel disease (IBD) and normal healthy controls stratified by MTHFR C677T variant

PF (μg/l)
Genotype IBD Controls p Value
TT4.40 (1.15–7.65)n=276.0 (3.96–10.40)n=70.01
CT5.56 (1.55–22.50)n=706.15 (2.20–16.10)n=380.90
CC6.05 (1.25–23.60) n=725.6 (1.90–17.75)n=420.50
  • IBD: TT versus CT, p=0.03; TT versus CC, p=0.03.

  • Controls: TT versus CT, p=0.8; TT versus CC, p=0.9.