Table 1

Prevalence and characteristics of selected histological parameters in patients with tuberculous (TB) and Crohn’s (CD) colitis

ParametersAll patientsAll biopsy specimensEndoscopically abnormal mucosaEndoscopically normal mucosa
TB (n=20)CD (n=20)p ValueTB (n=61)CD (n=112)p ValueTB (n=43)CD (n=49)p ValueTB (n=18)CD (n=63)p Value
Granulomas100%55%0.00061-150 46%14%0.00001-150 63%27%0.00041-150 5%5%1.0000
Average size of granulomas (μm)193950.00011-150 204.94102.080.00011-150 207.90101.630.00031-150 125.00104.170.6547
Granuloma >200 μm90%5%0.00001-150 33%1%0.00001-150 47%2%0.00001-150 0%0%
Average no of granulomas/section5.350.750.00071-150 4.821.440.00251-150 4.961.540.00661-150 111.0000
>5 granulomas/section40%0%0.00161-150 18%0%0.00001-150 26%0%0.00021-150 0%0%
Caseation40%0%0.00161-150 13%0%0.00021-150 19%0%0.00151-150 0%0%
Confluence60%0%0.000015%0%0.00011-150 21%0%0.00061-150 0%0%
Location of granuloma
 Mucosa70%50%0.196723%13%0.074533%22%0.27685%5%1.0000
 Submucosa45%5%0.00341-150 18%6%0.00001-150 25%2%0.00081-150 0%0%
 Granulation tissue50%15%0.01811-150 23%2%0.00001-150 33%4%0.00031-150 0%0%
Microgranulomas5%40%0.00981-150 2%9%0.05282%8%0.22400%10%0.2093
Ulcers75%65%0.490144%15%0.00001-150 60%33%0.00751-150 5%2%0.3972
 Aphthous5%5%0.24352%1%0.58222%0%0.46730%2%0.7777
 Deep80%50%0.04671-150 41%11%0.00001-150 58%24%0.00101-150 0%0%
 With epithelioid histiocytes45%5%0.00341-150 15%2%0.00001-150 21%2%0.00401-150 0%0%
Architectural alteration65%75%0.49011-150 41%40%0.917953%57%0.724911%30%0.1371
Chronic inflammation90%90%0.697551%75%0.00121-150 67%80%0.185411%71%0.00001-150
Discontinuous inflammation50%50%1.000023%19%0.511030%31%0.96855%10%0.5108
Focally enhanced colitis20%50%0.04671-150 7%14%0.12879%24%0.05510%6%0.3580
Disproportionate submucosal inflammation65%5%0.00011-150 25%2%0.00001-150 35%2%0.00000%0%
  • 1-150 p<0.05.