Table 3

Age and sex adjusted relative risk and 95% confidence interval of individual fracture types compared with normal controls, before and after diagnosis

Fracture type Crohn's disease Ulcerative colitis
Before diagnosis
 All fracture types0.7 (0.6 to 1.0)3-150[91]0.9 (0.7 to 1.1) [121]
After diagnosis
 All fracture types1.7 (1.2 to 2.3)3-150 [51]1.1 (0.8 to 1.6) [37]
 All fracture types (women)2.5 (1.7 to 3.6)3-150 [46]1.1 (0.7 to 1.8) [20]
 All fracture types (premenopausal women)2.9 (1.8 to 4.8)3-150 [32]1.4 (0.7 to 2.5) [15]
 All fracture types (postmenopausal women)1.8 (1.0 to 3.3)3-151[14]0.6 (0.3 to 1.6) [5]
 All fracture types (men)0.6 (0.3 to 1.3) [6]1.4 (0.8 to 2.3) [17]
 Skull and jaws1.1 (0.1 to 15.4) [1]0.0 [0]
 Spine6.7 (2.1 to 21.7)3-150 [5]2.4 (0.5 to 11.9) [2]
 Forearm2.0 (0.8 to 5.1) [8]1.2 (0.1 to 13.8) [5]
 Upper arm1.1 (0.7 to 1.7) [3]0.3 (0.1 to 1.7) [1]
 Hand and fingers1.4 (0.2 to 9.4) [9]1.3 (0.1 to 17.2) [9]
 Femur1.5 (0.2 to 11.7) [2]0.6 (0.1 to 4.9) [1]
 Lower leg1.1 (0.3 to 4.6) [5]1.5 (0.4 to 5.3) [7]
 Feet and toes3.3 (1.5 to 7.5)3-150 [11]1.7 (0.5 to 6.5) [6]
 Clavicles0.0 [0]1.5 (0.1 to 19.6) [3]
 Other (ribs and pelvis)4.9 (1.8 to 13.3)3-150 [7]2.1 (0.4 to 12.8) [3]

  • Numbers in square brackets are actual number of fractures.

  • ↵3-150 p<0.01 compared with normal controls.

  • ↵3-151 Borderline insignificant (p=0.061).