Table 2

In vivo and in vitro interleukin (IL) 1β and IL-8 production

UnitcagA+
DU
cagA+ gastritiscagA− gastritiscagA+ DU v gastritis p value2-150 Gastritis cagA+ v cagA− p value2-150
IL-8
Antrum
 In vivopg/mg protein120.859.30.0<0.001<0.003
 In vivo per H pylori pg/cfu × 105 18.813.70.00.12<0.0001
 In vitropg/ml347132787240.67<0.0001
Corpus
 In vivopg/mg protein25.979.20.0<0.0001<0.0001
 In vivo per H pylori pg/cfu × 105 7.315.10.0<0.01<0.0001
 In vitropg/ml342034686220.78<0.0001
IL-1β
Antrum
 In vivopg/mg protein81.656.524.8<0.0001<0.0001
 In vivo per H pylori pg/cfu × 105 5.63.84.20.11<0.0001
 In vitropg/ml
Corpus
 In vivopg/mg protein33.679.534.4<0.0001<0.0001
 In vivo per H pylori pg/cfu × 105 1.310.40.0<0.0001<0.003
 In vitropg/ml
  • 2-150 By Mann-Whitney test.

  • All values presented as medians.

  • DU, duodenal ulcer.