Effect of igmesine (1 mg/kg intravenously) on Escherichia coli heat labile (LT) and heat stable (STa) enterotoxin induced jejunal net secretion of electrolytes
| Net Cl−flux (μmol/min/g) | Net Na+flux (μmol/min/g) | Net K+flux (μmol/min/g) | Number | |
|---|---|---|---|---|
| LT | −19 (−28 to −17) | −20 (−24 to −18) | −1.1 (−1.4 to −0.8) | 16 |
| LT + igmesine | −152-150 (−18 to −13) | −102-150 (−13 to −5) | −0.62-150 (−0.8 to −0.5) | 9 |
| STa | −11 (−14 to −10) | −18 (−20 to −15) | −1.3 (−1.5 to −1.1) | 8 |
| STa + igmesine | −5.3† (−6 to −5) | −7.6† (−9 to −6) | −0.6† (−0.6 to −0.6) | 5 |
Data expressed as median (interquartile range).
↵2-150 p<0.02 compared with LT, †p<0.02 compared with STa (Mann-Whitney test).