Distribution and type of 21 K-ras mutations in DNA from microdissected areas
| Type of lesion | Codon 12 | Codon 13 |
|---|---|---|
| Patient 2 | ||
| Carcinoma, 4 areas | GGC→GAC × 44-150 | |
| Non-villous, hypermucinous, without dysplasia | GGT→TGT | |
| Patient 3 | ||
| Carcinoma K-ras mutation negative | ||
| High grade dysplasia near carcinoma | GGT→GTT | |
| Villous, hypermucinous, indefinite dysplasia | GGC→GAC | |
| Patient 6 | ||
| Tubulovillous DALM, high grade | GGT→GAT | |
| High grade dysplasia near DALM | GGT→GCT | |
| High grade dysplasia near DALM | GGT→GCT | |
| Patient 7 | ||
| Regeneration, no dysplasia | GGT→GAT | |
| Patient 9 | ||
| Villous, hypermucinous, indefinite dysplasia | GGT→AGT | |
| Villous, hypermucinous, indefinite dysplasia | GGT→AGT | |
| Patient 10 | ||
| Low grade dysplasia | GGT→GAT | |
| Villous, hypermucinous, indefinite dysplasia | GGT→GAT | |
| Patient 11 | ||
| Non-villous, hypermucinous, without dysplasia | GGT→GAT | |
| Villous, hypermucinous, indefinite dysplasia | GGT→AGT | |
| Villous, hypermucinous, indefinite dysplasia | GGT→AGT | |
| Villous, hypermucinous, indefinite dysplasia | GGT→AGT | |
| Villous, hypermucinous, indefinite dysplasia | GGT→AGT | |
| Flat lesion, indefinite dysplasia | GGT→GAT |
↵4-150 Identical mutation at different levels. DALM, dysplasia associated lesion or mass.