Course and outcome of patients who underwent transplantation (patients 1–8 from table 1)
| Patient | ||||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
| Sex | Female | Female | Female | Male | Female | Male | Female | Female |
| Manometry | Neuropathic | Myopathic | Neuropathic | Myopathic | Myopathic | Neuropathic | Neuropathic | Neuropathic |
| Pathology | Increased AChE+ fibres in SB mucosa | Atrophy and vaculoations of muscle | AChE+ fibres in SB mucosa | No pathological changes | No pathological changes | Neuronal dysplasia | No ganglia, antiganglia antibodies | Hypertrophic AChE+ fibres |
| Age at transplant | 11 y | 4.5 y | 11 y | 5 y | 23 m | 4.5 y | 18 y | 11 y |
| Organs received | Stomach, SB, liver | Stomach, SB, liver, colon | Stomach, SB, liver | Stomach, SB, liver | Stomach, SB, liver | SB | Stomach, SB, liver | Stomach, SB, liver |
| Cold ischaemia time (h) | 9.6 | 8 | 6.3 | 10.6 | 9.2 | 6.9 | 9.7 | NA |
| Follow up | 4.5 y | 5 y | 5 y | 7 m | 2 m | 1 y | 2.5 y | 2 y |
| Postoperative problems | Bezoar | Bezoar, urinary tract infection | Narcotic withdrawal, pancreatitis, MBP | Exfoliative rejection | Urinary tract infection, rejection | Achalasia, narcotic withdrawal | Dumping syndrome | |
| Outcome | Alive | Alive | Died 4 y after TX | Died 7 m after TX | Died 2 m after TX | Alive | Alive | Alive |
| Ostomies | No | G tube, ileostomy | G tube, ileostomy | G tube, ileostomy | G tube, J tube, ileostomy | No | J tube, ileostomy | J tube, ileostomy |
| School | Yes | Yes | Yes | Yes | Yes | |||
| Nutrition | Eating | Eating | Eating/partial enteral feeds | Off TPN until rejection | Enteral feeds at death | Eating | Eating, J tube for fluid replacement | Eating, J tube for fluid replacement |
AChE, acetylcholinesterase; SB, small bowel; TX, transplant; MBP, Munchausen syndrome by proxy.