Table 1

Baseline features of 200 patients with cirrhosis type B (Child A) according to hepatitis delta virus (HDV) and hepatitis B e antigen (HBeAg) status

Anti-HDV+/HBeAg− (n = 37) Anti-HDV+/HBeAg+ (n = 2) Anti-HDV−/HBeAg− (n = 116) Anti-HDV−/HBeAg+ (n = 45) p Value
Patient characteristics
 Male (%)761009087 NS
 Age (years)34 (13–62)25 (23–28)49 (23–75)47 (11–78)0.0001
Source of infection
 Household contact4 (11)1 (50)1 (1)1 (2)0.004
 Vertical transmission1 (3)03 (3)2 (4)
 Sexual transmission005 (4)6 (13)
 Medical exposure2 (5)02 (2)3 (7)
 Blood transfusion1 (3)02 (2)3 (7)
 Drug addiction2 (5)1 (50)1 (1)0
 Unknown27 (73)0102 (87)30 (67)
Biochemistry
 AST:ALT ratio0.8 (0.19–1.54)0.65 (0.48–0.82)0.86 (0.19–2.94)0.72 (0.09–2.14) NS
 Bilirubin (μmol/l)15 (5.9–35.7)14.2 (13–15.4)14 (5–51)13.6 (2.3–38.5) NS
 Albumin (g/l)41 (29–48)45.5 (43–48)40 (25–52.4)41 (27.3–53.3) NS
 γ-globulin (g/l)21 (9–46)19 (12–26)16 (7–39.7)16.8 (7.9–38)0.012
 Platelets (109/l)131 (38–276)238 (216–261)150 (31–340)160 (68–287) NS
  • For statistical analysis, three groups were considered: anti-HDV+/HBeAg−, anti-HDV−/HBeAg−, and anti-HDV−/HBeAg+.

  • p Value derived from analysis of variance or χ2 test.

  • Data are expressed as median (range) or as number of patients (%).

  • anti-HDV, antibody to HDV; NS, non significant; ALT, alanine aminotransferase; AST, aspartate aminotransferase.