Histological hepatic iron content score
| Iron cell location | Iron distribution in cirrhosis | ||
| Hepatocyte | Perinodular | Centronodular | |
| Absent | 0 | 0 | |
| Faint staining | 3 | 3 | |
| Non-confluent granules | 6 | 6 | |
| Confluent granules | 9 | 9 | |
| Sinusoidal cells | Perinodular | Centronodular | |
| Absent | 0 | 0 | |
| Faint staining | 1 | 1 | |
| Non-confluent granules | 2 | 2 | |
| Confluent granules | 3 | 3 | |
| Fibrosis | Absent | Focal | Diffuse |
| Macrophages | 0 | 1 | 3 |
| Biliary cells | 0 | 1 | 3 |
| Endothelial cells | 0 | 1 | 3 |
Iron deposits were assessed according to Deugnier's criteria10 which were adjusted for cirrhotic samples. Ranges: hepatocyte iron score, 0–18; sinusoid iron score, 0–6; fibrosis iron score, 0–9; total iron score, 0–33.