Table 1

Clinical and pathological features of 159 patients with T3,N0,M0 colorectal cancer stratified by replication error (RER) status

RER− cancers (n=137) RER+ cancers (n=22) p Value
Age (y) median (IQ range)70 (60–75)67 (64–73)0.891-150
Sex
Male69 (50%)13 (59%)0.481-151
 Female68 (50%)9 (41%)
Tumour site
Right colon44 (29%)13 (59%)0.0061-151
 Left colon/rectum97 (71%)9 (41%)
 Tumour size (cm) median (IQ range)5.0 (3.5–6.0)6.0 (5.0–8.0)0.011-150
Tumour differentiation
Well7 (5%)00.00081-152
 Moderate123 (90%)16 (73%)
 Poor7 (5%)6 (27%)
  • 1-150 Wilcoxon's rank sum test.

  • 1-151 χ2 test.

  • 1-152 χ2 test for trend.