Table 3

Clinical, pathological, and molecular features of 22 patients with replication error (RER) positive T3,N0,M0 colorectal cancers

Study number		Age		Sex		Tumour site		Tumour size (cm)		Tumour grade	Number of RER+ loci	K-ras mutation	Gene expression
Study number		Age		Sex		Tumour site		Tumour size (cm)		Tumour grade	Number of RER+ loci	K-ras mutation	p53	c-erbB-2	c-myc
6	69.6	Male	Caecum	3.0	Moderate	2	−	+	NA	NA
16	49.9	Male	Transverse colon	8.0	Poor	2	−	−	NA	NA
30	71.9	Male	Sigmoid colon	6.0	Moderate	3	−	−	−	+
34	77.2	Male	Transverse colon	8.0	Moderate	2	−	−	+	+
36	84.1	Male	Caecum	NA	Moderate	4	−	+	+	+
49	69.6	Female	Ascending colon	7.0	Moderate	2	−	+	+	+
50	82.8	Female	Caecum	5.0	Poor	2	−	+	+	−
51	72.0	Male	Rectum	6.0	Moderate	2	−	−	+	+
52	64.5	Female	Sigmoid colon	3.0	Moderate	2	+	+	+	+
53	64.8	Female	Ascending colon	8.0	Poor	3	−	+	+	+
69	63.6	Female	Rectum	4.0	Poor	2	−	+	+	+
73	73.2	Male	Transverse colon	8.0	Poor	4	−	−	+	+
81	74.0	Male	Sigmoid colon	7.0	Moderate	2	−	−	−	−
107	67.4	Female	Ascending colon	9.5	Poor	3	−	+	−	+
115	59.0	Male	Rectum	11.0	Moderate	2	−	−	+	−
129	54.2	Female	Rectum	7.0	Moderate	2	+	+	−	−
135	51.5	Female	Rectum	6.0	Moderate	3	−	+	−	−
138	74.9	Female	Caecum	5.0	Moderate	3	+	−	−	+
139	67.1	Male	Ascending colon	3.0	Moderate	3	−	+	+	−
143	73.1	Male	Caecum	6.0	Moderate	3	−	−	−	+
148	64.4	Male	Rectum	6.0	Moderate	2	−	−	−	+
153	62.7	Male	Ascending colon	5.0	Moderate	2	−	+	−	+