Table 3

Clinical, pathological, and molecular features of 22 patients with replication error (RER) positive T3,N0,M0 colorectal cancers

Study numberAgeSexTumour siteTumour size (cm)Tumour gradeNumber of RER+ lociK-ras mutationGene expression
p53c-erbB-2c-myc
669.6MaleCaecum3.0Moderate2+NANA
1649.9MaleTransverse colon8.0Poor2NANA
3071.9MaleSigmoid colon6.0Moderate3+
3477.2MaleTransverse colon8.0Moderate2++
3684.1MaleCaecumNAModerate4+++
4969.6FemaleAscending colon7.0Moderate2+++
5082.8FemaleCaecum5.0Poor2++
5172.0MaleRectum6.0Moderate2++
5264.5FemaleSigmoid colon3.0Moderate2++++
5364.8FemaleAscending colon8.0Poor3+++
6963.6FemaleRectum4.0Poor2+++
7373.2MaleTransverse colon8.0Poor4++
8174.0MaleSigmoid colon7.0Moderate2
10767.4FemaleAscending colon9.5Poor3++
11559.0MaleRectum11.0Moderate2+
12954.2FemaleRectum7.0Moderate2++
13551.5FemaleRectum6.0Moderate3+
13874.9FemaleCaecum5.0Moderate3++
13967.1MaleAscending colon3.0Moderate3++
14373.1MaleCaecum6.0Moderate3+
14864.4MaleRectum6.0Moderate2+
15362.7MaleAscending colon5.0Moderate2++
  • NA, data not available.