Table 2

Levels of IgG antibodies against synthetic tropomyosin peptide in sera from patients with ulcerative colitis, Crohn's disease, primary biliary cirrhosis, primary sclerosing cholangitis, and healthy volunteers

DiseaseAntibodies against synthetic peptide (active,inactive disease)Positivity2-a
Ulcerative colitis1.40 (0.52)2-150 2-152  (1.63 (0.52), 1.00 (0.44)2-151)2-150 68.8%
Crohn's disease0.50 (0.34)    (0.52 (0.34), 0.46 (0.37))15.4%
Primary biliary cirrhosis0.14 (0.09)0.0%
Primary sclerosing cholangitis1.61 (0.22)2-152 100.0%
Healthy volunteers0.32 (0.28)5.0%
  • Values represent optical density (OD) values at 405 nm.

  • 2-a Positivity: (number of patients whose OD value is higher than mean + 2 SD of healthy volunteers/number of patients examined)×100.

  • 2-150 p<0.05 compared with Crohn's disease;

  • 2-151 p<0.05 compared with active disease;

  • 2-152 p<0.05 compared with healthy volunteers.