Concentrations of proteins C, S, and antithrombin in different vascular beds
| Patient | Hepatic vein2-150 | Splenic vein2-151 | |||||
|---|---|---|---|---|---|---|---|
| PC | PS | AT | PC | PS | AT | ||
| 1 | 98 | 91 | – | ||||
| 2 | 78 | 96 | 102 | ||||
| 3 | 119 | 114 | 92 | ||||
| 4 | 96 | 92 | 89 | ||||
| 5 | 106 | 118 | 102 | ||||
| 6 | 82 | 100 | 140 | ||||
| 7 | 95 | 126 | 107 | ||||
| Liver disease2-152 | 90 | 98 | 100 | ||||
Concentrations of proteins C, S, and antithrombin measured in hepatic or splenic veins in individual patients with extrahepatic portal vein thrombosis (patients 1–3 and 5–7) or non-cirrhotic portal hypertension (patient 4), expressed as a percentage of concurrent peripheral vein levels. Patients 1–3 were sampled at the time of transjugular liver biopsy; patient 4 at the time of TIPSS insertion, and patients 5–7 at the time of splenorenal shunt surgery (all samples were taken prior to intervention).
↵2-152 Mean hepatic vein concentrations for 15 patients with intrinsic liver disease (mostly alcoholic cirrhosis) and portal hypertension (but without portal vein thrombosis) taken at the time of transjugular biopsy (n=13) or TIPSS insertion (n=2).
↵2-150 Hepatic versus peripheral vein concentrations in PVT group (p=0.27), and in liver disease group (p<0.01) (Wilcoxon rank sum).
↵2-151 Splenic versus peripheral vein concentrations in PVT group (p=0.14, Wilcoxon rank sum).
PC, protein C; PS, protein S; AT, antithrombin.