Table 1

Distribution of the −627 interkeukin (IL) 10 polymorphism in healthy controls and heavy drinkers with and without advanced liver disease

Subjects AAACCC
Controls (n=227)5 (2.2%)70 (30.8%)152 (67.0%)
AALD (n=287)19 (6.6%)125 (43.6%)143 (49.8%)1-150
NALD (n=107)3 (2.8%)36 (33.6%)68 (63.6%)
  • 1-150 Odds ratio (95% confidence interval) for possession of one or two A alleles versus controls: 2.04 (1.42 to 2.92); versus NALD: 1.76 (1.12 to 2.77).

  • AALD, advanced alcoholic liver disease; NALD, no evidence of alcoholic liver disease or steatosis only.