Comparison of metabolite ratios in patients and controls
| Regional metabolite ratios | Controls | Patients | p Value |
| Cortex | |||
| NAA/Cr | 2.2 (0.4) | 2.4 (0.5) | NS |
| Cho/Cr | 0.7 (0.3) | 0.4 (0.3) | <0.05 |
| Glx/Cr | 0.1 (0.1) | 0.5 (0.4) | <0.01 |
| Cerebellum | |||
| NAA/Cr | 2.1 (0.5) | 2.2 (1.0) | NS |
| Cho/Cr | 0.9 (0.3) | 0.6 (0.1) | <0.05 |
| Glx/Cr | 0.1 (0.1) | 0.5 (0.4) | <0.01 |
| Basal ganglia | |||
| NAA/Cr | 2.1 (0.5) | 2.0 (0.5) | NS |
| Cho/Cr | 0.9 (0.3) | 0.6 (0.2) | <0.05 |
| Glx/Cr | 0.1 (0.3) | 0.6 (0.2) | <0.001 |
Results expressed as mean (SEM).
Cho, choline containing compounds; Cr, creatine; Glx, glutamine/glutamate; NAA, N-acetylaspartate.