UC patients (n=10) | |||||
---|---|---|---|---|---|
UC patients with pouchitis (n=11) | UC patients without pouchitis (n=14) | FAP patient pouch samples (n=8) | Inflamed mucosa | Normal mucosa | |
MMP-1 | 17.7 (11.1–25.8)1-150 | 7.8 (4.9–13.1) | 7.6 (6.3–9.1) | 12.7 (9.9–47.1)1-150 | 6.5 (5.3–12.0) |
MMP-2 | 16.4 (12.2–23.4)1-150 | 9.5 (3.7–12.9) | 6.3 (4.7–23.4) | 27.8 (6.1–78.7)1-150 | 8.3 (4.2–12.1) |
MMP concentrations were determined by ELISA as described in material and methods. Values are median (minimum and maximum values).
↵1-150 p⩽0.05 compared with UC patients without pouchitis.