Endothelial expression of VCAM-1 (ng of mAb/g tissue) on different organs under basal unstimulated conditions (n=5) or five hours after TNF-α injection, in vehicle or heparin pretreated rats (n=4)
| Lung | Heart | Pancreas | Stomach | Small bowel | Caecum | Colon | Kidney | Muscle | |
|---|---|---|---|---|---|---|---|---|---|
| Basal | 195 (30) | 11.2 (0.4) | 8.4 (1.1) | 6.0 (1.3) | 6.3 (0.9) | 5.9 (0.8) | 3.3 (0.4) | 84.5 (10.5) | 2.6 (0.2) |
| TNF/vehicle | 361 (36)3-150 | 83.5 (1.5)3-150 | 43.5 (2.5)3-150 | 19.5 (0.5)3-150 | 38.5 (1.5)3-150 | 38.5 (0.5)3-150 | 28.0 (2.0)3-150 | 206 (5.5)3-150 | 14.0 (2.0)3-150 |
| TNF/heparin | 307 (2.5 | 78.5 (12)3-150 | 36.5 (1.5)3-150 | 19.0 (1.0)3-150 | 30.0 (3.0)3-150 | 33.5 (0.5)3-150 | 22.5 (2.5)3-150 | 199 (23)3-150 | 11.0 (1.0)3-150 |
↵3-150 p<0.05 v basal.