Adenovirus infusion | Normal | Cirrhotic | Fulminant |
AST (u/litre) | |||
Before | 68.8 (10.9) | 124.0 (33.40) | 3311.7 (1313.7) |
After | 156.1 (58.7)1-150 | 260.1 (91.2)1-150 | 159.3 (72.3)1-150 |
None | ND | ND | 177.9 (67.0)1-150 |
ALT (u/litre) | |||
Before | 24.3 (4.2) | 51.0 (16.1) | 4469.0 (1737.6) |
After | 30.7 (10.0) | 84.0 (25.8)1-150 | 47.3 (38.8)1-150 |
None | ND | ND | 87.0 (40.1)1-150 |
LDH (u/litre) | |||
Before | 724.8 (252.5) | 712.3 (281.3) | 9094.7 (2857.9) |
After | 2045.0 (331.9)1-150 | 1624.1 (528.7)1-150 | 1660.3 (836.7)1-150 |
None | ND | ND | 1441.3 (916.8)1-150 |
↵1-150 Data are mean (SD) of eight animals.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase, all expressed as units per litre at 37°C.
*Significantly different (p<0.05) from before administration of adenovirus, using Welch's t test.
ND, not done.