Table 1

Serological, histological, and HLA typing of the unrelated HBV positive chronically infected individuals

Subject NoHLA-AHLA-BHBV serologyALT (iu/l)HBV DNALiver biopsy
12, 37, 44HBsAg/anti-HBe pos57NegChronic active hepatitis
22, 247, 51HBsAg/anti-HBe pos87NegChronic active hepatitis
32, 307, 18HBsAg/anti-HBe pos21Negnd
41, 27, 13HBsAg/HBeAg pos2301680 pg/mlChronic active hepatitis
52, 1135, 61HBsAg/anti-HBe pos15Negnd
62, 2835, 51HBsAg/anti-HBe pos67NegInactive cirrhosis
72, 318, 51HBsAg/anti-HBe pos28NegMild hepatitis
  • Serum alanine transaminase (ALT, normal range 5–40 iu/l) and serum hepatitis B virus (HBV) DNA measurements (branched chain DNA assay; Chiron Corporation, Emeryville, California, USA) are shown. Liver biopsy findings are shown where performed (nd indicates liver biopsy not performed).

  • HBV, hepatitis B virus; HBe, hepatitis B e; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; pos, positive; Neg, negative.