Table 1

Relationship between serum ferritin, transferrin saturation and mutation

GenotypeNo of patientsAge (y)Serum ferritin (μg/l)1-a Transferrin saturation (%)1-b
Normal1456 (23–70)781 (213–1560)71 (61–82)
Homozygous for C282Y957 (43–70)1580 (434–3292) p=0.0471-150 80 (68–92) ns
Heterozygous for C282Y245 (28–70)799 (241–1357) ns65 (61–69) ns
Heterozygous for H63D549(40–67)2240(1450–6260) p<0.021-150 77 (74–82) ns
Double heterozygous335(28–42)681(409–952) ns74 (71–76) ns
  • Values are (mean (range)).

  • 1-a Reference range: M:20–284 μg/l, F:8–186 μg/l;

  • 1-b Reference range: 13–53%.

  • 1-150 Significant difference compared with the normal genotype group.