Amsterdam criteria for hereditary non-polyposis colorectal cancer
| • At least three relatives with CRC |
| • One should be first degree relative of other two |
| • At least two successive generations affected |
| • At least one CRC diagnosed before age 50 |
| • FAP excluded |
| • Diagnosis confirmed by histology |
CRC, colorectal cancer; FAP, familial adenomatous polyposis.