Time/activity curve parameters for99mTc-DISIDA biliary scanning with and without morphine provocation in patients with normal (group I) and elevated (>40 mm Hg) (group II) sphincter of Oddi basal pressure
Group I | Group II | p Value | |
n | 16 | 18 | |
Without morphine provocation | |||
Tmax (minutes) | 16 (12–29) | 22 (10–63) | 0.07 |
E45 (%) | 37.2 (10.2–58.4) | 26.7 (0–62.3) | 0.2 |
E60 (%) | 55.5 (30.1–70.5) | 38.8 (0–74.5) | 0.1 |
With morphine provocation | |||
Tmax (minutes) | 30.5 (18–49) | 39.5 (23–70) | 0.03 |
E45 (%) | 9.5 (0–24.9) | 1.8 (0–33.7) | 0.04 |
E60 (%) | 28.2 (3.5–43.6) | 4.9 (0–51.6) | 0.002 |
Values are median (range).
Tmax refers to time to maximal activity and E45 and E60 refer to the percentage of maximal activity cleared (emptied) from the biliary system at 45 and 60 minutes, respectively.