Sensitivity, specificity, and positive and negative predictive values of Ki-ras point mutation detected in bile specimens and non-surgical histological results (histology) in the diagnosis of malignant versus benign biliary strictures
| Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
| SSOH | 17 | 96 | 94 | 15 |
| PCR-MASA | 24 | 96 | 95 | 23 |
| SSOH and PCR-MASA | 25 | 96 | 96 | 25 |
| Histology | 59 | 100 | 100 | ND |
| Histology and Ki-rasmutations | 73 | 96 | 97 | ND |
PPV, positive predictive value; NPV, negative predictive value; ND, not done.
SSOH, sequence specific oligonucleotide hybridisation; PCR-MASA, polymerase chain reaction- mutant allele specific amplification.