Table 1

Sensitivity, specificity, and positive and negative predictive values of Ki-ras point mutation detected in bile specimens and non-surgical histological results (histology) in the diagnosis of malignant versus benign biliary strictures

Sensitivity (%)Specificity (%)PPV (%)NPV (%)
SSOH and PCR-MASA25969625
Histology and Ki-rasmutations739697ND
  • PPV, positive predictive value; NPV, negative predictive value; ND, not done.

  • SSOH, sequence specific oligonucleotide hybridisation; PCR-MASA, polymerase chain reaction- mutant allele specific amplification.